When will the FDA approve COMP360 Psilocybin for Treatment-Resistant Depression?

Prediction markets currently give a 59% probability that When will the FDA approve COMP360 Psilocybin for Treatment-Resistant Depression?. This contract trades at 59¢ on Kalshi, closing October 1, 2027. The market has experienced notable upward momentum, rising from 34¢ to 41¢ over seven days before settling at 35¢, suggesting recent volatility around FDA approval expectations for this psychedelic therapy.

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59¢
Bid/Ask 48/93¢·Spread 45¢·Vol $181.42·OI $1,119·Closes Oct 1, 2027·520d remaining
KXFDAAPPROVALDATECMPS-360-27OCT01
7-day price142 snapshots · 7 regime
63¢47¢ current
Apr 82¢Apr 29

Analysis

12d ago

The market has experienced notable upward momentum, rising from 34¢ to 41¢ over seven days before settling at 35¢, suggesting recent volatility around FDA approval expectations for this psychedelic therapy. With only $5 in 24-hour volume against $471 open interest, liquidity is extremely thin, making the 3¢ spread potentially misleading for actual execution prices. The 98.7% implied yield on Yes positions reflects the asymmetric risk profile typical of binary FDA approval bets, though the neutral regime score and 532 days to expiry suggest the market may be pricing in genuine uncertainty rather than imminent approval catalysts.

Resolution rules

If the FDA approves COMP360 Psilocybin for Treatment-Resistant Depression for marketing before Oct 1, 2027, then the market resolves to Yes.

Indicators

IY (Yes) 79.2%
IY (No) 62.3%
Adj IY 40%
CRI 1
Overround 0.2%
▶ Full indicator table (5)
IndicatorValue
IY (Yes)79.2%
IY (No)62.3%
Adj IY40%
CRI1
Overround0.2%

Regime

Label
neutral
Score
0.5
Spread
45¢
Computed
4/29/2026, 9:39:22 AM
Indicators computed 4/29/2026, 9:38:26 AM

Trade

View on kalshisf trade KXFDAAPPROVALDATECMPS-360-27OCT01 yes 100

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