When will the FDA approve COMP360 Psilocybin for Treatment-Resistant Depression?

Prediction markets currently give a 99% probability that When will the FDA approve COMP360 Psilocybin for Treatment-Resistant Depression?. This contract trades at 99¢ on Kalshi, closing July 1, 2027. The market has experienced significant recent volatility, with the price declining 32% over seven days from 17¢ to 25¢, suggesting weakening conviction in near-term FDA approval odds despite COMP360's clinical progress.

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99¢
Bid/Ask 39/98¢·Spread 59¢·Vol $1,428.65·OI $3,028.01·Closes Jul 1, 2027·428d remaining
KXFDAAPPROVALDATECMPS-360-27JUL01
7-day price107 snapshots · 19 regime
45¢39¢ current
Apr 111¢Apr 29

Analysis

12d ago

The market has experienced significant recent volatility, with the price declining 32% over seven days from 17¢ to 25¢, suggesting weakening conviction in near-term FDA approval odds despite COMP360's clinical progress. The 8¢ spread and minimal liquidity ($751 open interest) create execution challenges, though the asymmetric implied yields (377.7% for Yes versus 18.2% for No) indicate the market is pricing substantial approval risk within the 440-day window. The moderate cliff risk index of 5 and neutral regime suggest this is a genuine uncertainty market rather than one driven by imminent catalysts, making the recent price drop potentially meaningful for contrarian positioning.

Resolution rules

If the FDA approves COMP360 Psilocybin for Treatment-Resistant Depression for marketing before Jul 1, 2027, then the market resolves to Yes.

Indicators

IY (Yes) 133.5%
IY (No) 54.6%
Adj IY 0%
CRI 2
Overround 0.2%
LAS 1.56
▶ Full indicator table (6)
IndicatorValue
IY (Yes)133.5%
IY (No)54.6%
Adj IY0%
CRI2
Overround0.2%
LAS1.56

Regime

Label
neutral
Score
0.5
Spread
59¢
Computed
4/29/2026, 9:39:43 AM
Has orderbookIndicators computed 4/29/2026, 9:38:26 AM

Trade

View on kalshisf trade KXFDAAPPROVALDATECMPS-360-27JUL01 yes 100

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