When will Intellia Therapeutics, Inc. submit a BLA for Lonvoguran Ziclumeran (lonvo-z) to the FDA?

Prediction markets currently give a 70% probability that When will Intellia Therapeutics, Inc. submit a BLA for Lonvoguran Ziclumeran (lonvo-z) to the FDA?. This contract trades at 70¢ on Kalshi, closing December 1, 2026. The market is pricing a 53% probability of a BLA submission by end-2026, but the extremely high realized volatility (244%) and elevated implied yields (130.6% for Yes, 195.1% for No) suggest significant uncertainty around the binary outcome.

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70¢
Bid/Ask 70/71¢·Spread 1¢·Vol $0·OI $513.93·Closes Dec 1, 2026·216d remaining
KXNEWDRUGAPPNTLA-LONV-26DEC01
7-day price506 snapshots · 8 regime
70¢70¢ current
Apr 1053¢Apr 28

Analysis

12d ago

The market is pricing a 53% probability of a BLA submission by end-2026, but the extremely high realized volatility (244%) and elevated implied yields (130.6% for Yes, 195.1% for No) suggest significant uncertainty around the binary outcome. With near-zero 24-hour volume and only $510.93 open interest, liquidity is critically low, making the 7¢ spread potentially misleading—the true execution cost could be substantially higher, and the recent price movement from 53¢ to 57¢ may reflect thin-market noise rather than meaningful information arrival.

Resolution rules

If Intellia Therapeutics, Inc. submits a BLA for Lonvoguran Ziclumeran (lonvo-z) to the FDA before Dec 1, 2026, then the market resolves to Yes.

Indicators

IY (Yes) 72.3%
IY (No) 393.9%
Adj IY 197%
CRI 2
Overround 2.4%
▶ Full indicator table (5)
IndicatorValue
IY (Yes)72.3%
IY (No)393.9%
Adj IY197%
CRI2
Overround2.4%

Regime

Label
neutral
Score
0.5
Spread
1¢
Computed
4/29/2026, 9:39:19 AM
Observability mediumEvent type scientific
Indicators computed 4/29/2026, 9:38:26 AM

Trade

View on kalshisf trade KXNEWDRUGAPPNTLA-LONV-26DEC01 yes 100

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